Protein name:
Mitogen-activated protein kinase kinase kinase 8 ;
Alternative:
Tumor progression locus 2 (TPL-2) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Forms a ternary complex with NFKB1 and TNIP2.
Function:
Required for TLR4 activation of the MEK/ERK pathway. Able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105. Plays a role in the cell cycle.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MEYMSTGSDE | KEEIDLLINH | LNVSEVLDIM | ENLYASEEPA | VYEPSLMTMC |
100:
PDSNQNKEHS | ESLLRSGQEV | PWLSSVRYGT | VEDLLAFANH | ISNTTKHFYR |
150:
CRPQESGILL | NMVISPQNGR | YQIDSDVLLV | PWKLTYRSIG | SGFVPRGAFG |
200:
KVYLAQDMKT | KKRMACKLIP | VDQFKPSDVE | IQACFRHENI | AELYGAVLWG |
250:
DTVHLFMEAG | EGGSVLEKLE | SCGPMREFEI | IWVTKHVLKG | LDFLHSKKVI |
300:
HHDIKPSNIV | FMSTKAVLVD | FGLSVQMTED | VYLPKDLRGT | EIYMSPEVIL |
350:
CRGHSTKADI | YSLGATLIHM | QTGTPPWVKR | YPRSAYPSYL | YIIHKQAPPL |
400:
EDIAGDCSPG | MRELIEAALE | RNPNHRPKAA | DLLKHEALNP | PREDQPRCQS |
450:
LDSALFDRKR | LLSRKELELP | ENIADSSCTG | STEESEVLRR | QRSLYIDLGA |
467:
LAGYFNIVRG | PPTLEYG
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat Mitogen-activated protein kinase kinase kinase 8
ELISA Kit for Rat Mitogen-activated protein kinase kinase kinase 8
ELISA Kit for Rat Mitogen-activated protein kinase kinase kinase 8
CLIA Kit for Rat Mitogen-activated protein kinase kinase kinase 8
CLIA Kit for Rat Mitogen-activated protein kinase kinase kinase 8
CLIA Kit for Rat Mitogen-activated protein kinase kinase kinase 8
Polyclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 8
Polyclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 8
Polyclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 8
Monoclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 8
Monoclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 8
Monoclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 8
Protein for Rat Mitogen-activated protein kinase kinase kinase 8
Protein for Rat Mitogen-activated protein kinase kinase kinase 8
Protein for Rat Mitogen-activated protein kinase kinase kinase 8
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
strain :
Long Evans .
tissue :
Liver .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH NFKB1